AREDS Report #6
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Figure 1.
The Age-Related Eye Disease Study maculopathy grading grid,
affixed to the photograph of a left eye without age-related
macular degeneration. The grid is composed of three circles
concentric with the center of the macula and four radial lines
in the 1:30, 4:30, 7:30, and 10:30 meridians. The radius of the
inner circle corresponds to 1/3 disk diameter in the fundus of
an average eye, the radius of the middle circle to 1 disk diameters,
and the radius of the outer circle to 2 disk diameters, yielding areas
of 4/9 disk diameter, 4 disk diameters and 16 disk diameters,
respectively. Nominally these distances are referred to as the
500 um, 1500 um, and 3000 um, respectively, in accordance with
the longstanding clinical convention, even though a more accurate
estimate of the average disk diameter is 1800 to 2000 um. Thus the
grid defines nine sub-fields: central; inner superior, inner nasal,
inner inferior, and inner temporal; outer superior, outer nasal,
outer inferior, and outer temporal. Two segments of a horizontal
line project from the outermost circle so that the grid can be aligned
with the horizontal meridian of the fundus as it is centered over the macula.
| JPEG (low res) | TIF (high res) |
| Figure 1 | Figure 1 (3.5mb) |
Figure 3.
Fundus photographic examples illustrate the longitudinal application of the age related
eye disease study age-related macular degeneration grading system, showing how retinal
changes are reflected in movement on the grading scales. (top left and right) A left eye
with expansion of the area involved by drusen in the center and inner subfields
(central zone), from total area grater than or equal to circle I-1 but less than O-2 (code 4)
at baseline (top left) to total area greater than or equal to 1 disk area (code 7) at the 4
year visit (top right). (Bottom left and right) A left eye with retinal pigment epithelial
abnormalities in the central zone. At baseline (bottom left) there are several foci of
increased pigment (the most prominent indicated by an arrow), with total area greater than
circle C-1 but less than C-2 (code 4). There are many drusen (some prominent and some faint)
but no retinal pigment epithelial depigmentation (code 0). At the 5 year visit (bottom right)
there are more foci of increased pigment, with total are now greater than or equal to circle
C-2 but less than O-2 (code 5), and there are now several areas of decreased retinal pigment
epithelial pigmentation (arrow) with a total area greater than or equal to 1 disk area but less
than 2 disk areas (code 6). The most superior area of decreased pigmentation is almost pronounced
enough to be classified as geographic atrophy.
| JPEG (low res) | TIF (high res) |
| Figure 3 | Figure 3 (12mb) |
Copyright © 2001
Fundus Photograph Reading Center
Department of Ophthalmology and Visual Sciences
University of Wisconsin - Madison
The University of Wisconsin-Madison is an equal opportunity educator and employer
Fundus Photograph Reading Center
Department of Ophthalmology and Visual Sciences
University of Wisconsin - Madison
The University of Wisconsin-Madison is an equal opportunity educator and employer